Aprile Pilon
Founder & Chief Executive Officer Trove
Dr. Pilon is a multi-functional executive with 25 years of broad-based entrepreneurial experience in the biopharmaceutical industry, including project management, fundraising, team building, corporate governance, licensing and IP strategy, regulatory submissions, directing R&D, clinical trial management, and business development. She is also an accomplished scientist, an inventor on over 30 issued patents and several pending patents, and principal investigator on several USG grants. Dr. Pilon is Trove’s founder and also a member of the Company’s board of directors.
Dr. Pilon holds a B.A. in Physics from Wheaton College and a Ph.D. in Molecular and Cell Biology from the Pennsylvania State University. She trained as a post-doctoral fellow at the National Institutes of Health before joining the biotech industry in 1992.
Seminars
- Understand how loss of airway epithelial integrity, reflected by reduced CC16 levels, defines biologically distinct COPD endotypes and enables patient stratification beyond symptoms and exacerbation history toward underlying disease mechanisms
- Gain insight into how CC16, when integrated with complementary biomarkers such as sRAGE and fibrinogen, informs prediction of lung function decline, emphysema progression, and therapeutic responsiveness using human translational and longitudinal datasets
- Highlighting how replacement and augmentation of SCGB1A1 directly targets epithelial dysfunction, inflammation, and fibrosis, supporting a disease‑modifying treatment strategy that goes beyond bronchodilation to preserve lung function and reduce exacerbation burden
