Sarah Sherlock
Head of Clinical Imaging AstraZeneca
Head of Clinical Imaging, Early Clinical Development, Respiratory & Immunology at AstraZeneca, with extensive experience integrating medical imaging into clinical trials. Brings deep expertise in imaging biomarkers, imaging vendor oversight, and the strategic application of imaging to support early clinical development and decision-making.
Seminars
Thursday 17th September 2026
Imaging Mucus Plugs in COPD: Quantitative Evaluation and Clinical Impact
9:00 am
- Mucus plugging can be identified and quantified reliably on CT using standardized definitions and reading processes, maximizing the value of imaging in clinical trials
- Emerging quantitative analysis approaches enable detailed assessment of mucus burden and spatial distribution, improving characterization and understanding of clinical impact
- Reductions in mucus plug burden have been observed after initiation of advanced therapies, supporting mucus plugging as a potential imaging marker of treatment response
